
What’s the significance of THC in medical treatments?
Most health practitioners believe this cannabinoid is an unexplored goldmine. Its interaction with the body’s endocannabinoid system (ECS) could be therapeutic. This interplay may influence various physiological processes.
Did you know 76% of healthcare professionals endorse medical cannabis use?¹ As of 2019, at least 2.7% of Australians were using this product.² In other words, around 600,000 people embrace this natural remedy.
There’s a sharp spike in medical cannabis prescriptions in Australia. More doctors continue to seek prescribing permits due to this herb’s potential. The grand question is, what’s the best way to dose medical cannabis?
Precise THC dosing is vital to producing optimal patient results. It maximises potential benefits while minimising risks.
Too little THC may pose inadequate symptom relief. Excessive dosing can lead to unwanted effects or worse symptoms. Striking an accurate balance is imperative.
Medical professionals should leverage the THC dosage chart for precise dosing. It’s a comprehensive tool that accounts for distinct patient parameters. It aims to help your patients maximise their cannabis experience.
Discover THC, its dosing factors, and how a dosage chart adds precision to treatment.
Understanding THC
THC is among the most abundant cannabinoids in the cannabis plant. It’s highly psychoactive, often producing euphoric effects in patients. It activates some brain parts to trigger the “high” sensation.
This cannabinoid primarily interacts with the body’s CB1 receptors. Their interplay mediates most effects in the central nervous system (CNS). CB1 receptors feature in neurons, helping modulate neurotransmission.³ They’re vital to memory and learning processes.
How does THC differ from other cannabinoids? It features in most cannabis varieties, making it the most prevalent cannabinoid.⁴ Most cannabis strains contain 10–30% THC content. THC is also typically more potent thanks to its psychoactive influence.
THC could have multifaceted relevance in medical applications. Scientists continue to explore its potential for various medical conditions.
This active compound may influence appetite, pain, movement, and memory.⁵ There’s growing evidence of THC’s applicability in some therapies.
Factors influencing THC dosage
What should guide your quest for precise THC dosing? Understand the factors below, which dictate this cannabinoid’s impact.
Patient-specific variables
A patient’s specific nuances can determine how much THC you administer to them. The main patient-specific variables to consider in your dosage include:
- Age, weight, and metabolism. As a patient gets older, their metabolism typically declines.⁶ They may break down THC rather slowly than younger users. Weight is also a factor, as THC is fat-soluble.⁷ It binds to fat molecules and stays longer in the body.
- Tolerance levels. Frequent cannabis use builds up tolerance in patients. Regular users may need higher doses to achieve the desired effects. Cannabis first-timers may show more sensitivity even to lower doses.
- Medical history and current conditions. THC may interact with some medicines by inhibiting their metabolism.⁸ It could also increase the sedation of CNS depressants.⁹ Apply caution for patients with psychosis, schizophrenia, and severe liver disease.¹⁰
Strain-specific considerations
Cannabis varieties differ in their THC content based on a host of factors. Here are the top strain-specific aspects to inform your patients’ dosage:
- THC content in different cannabis strains. Cannabis variants with 15–20% THC content are usually marked “potent”.¹¹ Percentages above this cap qualify as “very high.” OG strains like Ghost OG and OG Kush are among the most coveted for top THC levels.¹²
- Indica vs. sativa strains. Sativa cannabis variants usually boast higher THC content than indica strains.¹³ No wonder sativas are more mind-oriented and euphoric. Indicas are typically body-oriented and relaxing due to high CBD levels.
Administration methods
How do your patients prefer to ingest THC? These popular administration methods influence the onset and duration of effects:
- Smoking. This conventional ingestion route is the most popular for a reason.¹⁴ Combusting cannabis flowers releases cannabinoids immediately. It has a fast onset as effects appear in minutes. Sensations can last up to four hours.
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Vaporisation. Vaping isn’t necessarily combustion. It’s heating cannabis to a point where cannabinoids become vapour. Like smoking, it also boasts fast onset and easy titration.
- Edibles. These are cannabis-infused foods and drinks that offer a tasty alternative to inhalation. They have delayed onset of effects, ranging from 30 minutes to two hours.¹⁵ Results last for 4–8 hours.
- Tinctures. Patients typically ingest these cannabis liquid extracts under their tongues. They can also mix them with food and drinks. They come with droppers for precise dosing. Effects come on within 15–45 minutes.
- Topicals. Cannabis-infused balms, creams, and salves work directly on the skin. They’re suitable for localised pain and inflammation relief.¹⁶ Their effects have a slower onset, taking up to an hour to manifest.¹⁷

Establishing a baseline dosage
Unlocking THC precision begins with establishing a baseline dosage. Start low and go slow, as individual responses may vary. This cautious approach allows you to assess the patient’s medical cannabis tolerance. It ensures safety while minimising the risk of side effects.
Beginning with a lower dose allows the body to adjust gradually. It sets a foundation for observing individual reactions and enhancing patient experience. You can determine the optimal dosage range for desired therapeutic effects.
Properly employing the titration process leads to optimal results. This gradual adjustment of THC dosage doesn’t work in isolation. It also depends on patient feedback. Understanding individual needs and responses allows you to fine-tune therapy. It helps achieve more with less.
Regular and open communication with patients leads to a successful baseline THC dosage. Users get subjective experiences from THC. Urge patients to report changes in symptoms, side effects, or overall well-being.
THC dosage chart for various medical conditions
Developing a THC dosage chart takes a nuanced approach to cover most bases. Optimal doses for different medical conditions can vary based on:
- Individual patient characteristics
- Specific nature of the treated condition
Below is a roundup of typical THC dosages for different conditions in milligrams (mg).
Chronic pain management
Some studies claim cannabinoids may be effective at treating chronic pain. Their analgesic effects could inhibit pain pathways and reduce neural inflammation. The dilemma lies in the proper quantity to administer.
You can initiate your patient to a treatment regimen with equal THC-to-CBD ratios. Most start with a dose of 2.5–5 mg of each cannabinoid 1–2 times daily.¹⁸ Titrate this dose by 2.5–5 mg of each compound every 2–3 days.
This dosing routine isn’t cast in stone. THC dosing is highly variable depending on a patient’s condition. Sometimes, doses fall below 2.5 mg. Other times, they exceed the typical daily amount of 40 mg.
Remember to regularly monitor the patient’s pain levels and adjust dosage accordingly.
Anxiety and depression
Anecdotal evidence shows cannabis may alleviate anxiety and depression over time. How do you dose THC for these mood disorders?
Generally, THC could cause anxiety at higher doses and relieve it at lower doses.¹⁹ It’s an ideal remedy as it may trigger mood elevation. Scientists recommend a starting dose of 3 mg via edibles or tinctures. Vaping provides faster relief for sudden anxiety attacks.
Improper THC dosing could worsen anxiety and depression. Some users get panic attacks at elevated doses.²⁰ Mitigate these effects by sticking to low doses as you observe patient response. Warn your patients about the dangers of self-medicating mood disorders.
Nausea and vomiting
Some research reviews claim cannabinoids could mitigate cancer-related complications. Do your patients experience chemotherapy-induced nausea and vomiting? Consider optimal THC dosage for symptom relief.
Scientists recommend a balanced THC-to-CBD ratio for this particular application. Patients took concentrations of 2.5 mg thrice daily for up to five days.²¹ There was a significant reduction of emesis and nausea afterwards. Dizziness and sedation were the main side effects.
These findings suggest combining THC with other treatments may be effective.²² THC could suppress chemotherapy-induced emesis and induce appetite. It might complement cancer therapies in reducing discomfort during recovery.
Sleep disorders
Some research reviews hint at THC’s potential to ease sleep disorders. At lower doses, it impacts CB1 receptors to favour sleep patterns. The aftermath is:²³
- Reduced sleep onset latency
- Ease of falling asleep
- Increased slow-wave sleep
- Increased total sleep time
Recommend cannabis strains with THC content below 20% for insomnia patients.²⁴ A THC dose of 2 mg is a reasonable point to start.²⁵ For patients new to THC, lower doses are optimal enough. Oral intake is suitable as the effects come on more gradually and steadily.
Consider raising this dose by 50% the following night to improve the effects. Advise patients never to go beyond 10 mg of THC per ingestion.
Special considerations and patient education
What are the risks associated with high THC dosages?²⁶ Highly potent cannabis may promote tolerance buildup. Taking a break from regular use can trigger a series of withdrawal symptoms. These effects can be emotional, like irritability or psychological, like isolation.
Remember, there isn’t a one-size-fits-all standard for THC dosages. It’s imperative to educate your patients on responsible cannabis use. Emphasise the need for individualised treatment plans based on the patient’s nuances. Discuss with them their current conditions and tolerance.
Don’t forget to address concerns and misconceptions about THC. Help patients distinguish THC’s psychoactive and potential medicinal effects.
Reassure them that controlled THC use could be therapeutic rather than merely euphoric. Reiterate that higher doses don’t always mean better results. Provide evidence-based information to reinforce a practical THC perception.

Monitoring and adjusting dosages
Monitoring and adjusting THC dosages involves regular patient follow-ups. Schedule frequent appointments to assess the patient’s response to THC therapy. The frequency can vary based on the nature of the medical condition treated.
Regular consultations also allow you to evaluate the efficacy of the current dosage. It’s a window to monitor side effects and adjust dosages accordingly.
Support open communication to gauge the patient’s experience and feedback. It helps you find the dosage and product that best manages the patient’s condition. The aim is to minimise side effects as much as possible.
Legal and ethical considerations
The legal status of cannabis varies by jurisdiction. Areas like the Australian Capital Territory (ACT) permit recreational cannabis. A patient should be at least 18 to possess or consume this product. There are also quantity restrictions.
Compliance with local and national regulations ensures a positive cannabis experience. The Therapeutic Goods Administration (TGA) checks the safety of cannabis products.
Seek TGA’s permission to recommend THC for medicinal use. Comply with its prescribing, dispensing, and consumption standards.
Don’t forget ethical considerations when employing THC therapy. Seek informed consent before any prescriptions. Respect the patient’s choices regarding the treatment. Acknowledge THC’s limited research in medical applications to manage expectations. Mention its potential for abuse.
Remember, cannabis legislation is ever-evolving. Staying updated helps your practice remain compliant and authentic. Monitor local, state, and national changes to ensure ethical patient care.
Unlock the precision of THC dosages with PlantEd
While CBD steals the show for potential medicinal effects, THC may be equally capable. Ongoing research shows it could alleviate pain, anxiety, depression, and insomnia. Its effectiveness for these conditions varies by dosage.
Understanding optimal THC dosages can be a game-changer in your clinical practice. The ideal routine? Start with low doses then gradually titrate as you monitor patient response. Consider patient-specific variables, strain differences, and ingestion methods.
Different medical issues may demand varying THC doses. Develop a THC chart for diverse conditions like nausea, insomnia, pain, and anxiety. Discuss these options with your patients, taking an evidence-based tone.
As THC research gains momentum, collaboration in cannabinoid medicine is critical. It’s a solid avenue for creating standardised THC dosing guidelines. This approach ensures safe and effective therapeutic applications.
Where do you begin? Start by working closely with Planted as your go-to cannabis resource hub. Contact us today to discuss our accredited cannabis courses spanning dynamic topics.
References
- Castillo, M. (2013, May 31). Survey: 76 percent of doctors approve of medical marijuana use. Cbsnews.com. https://www.cbsnews.com/news/survey-76-percent-of-doctors-approve-of-medical-marijuana-use/
- Ritchie, P. (2022, December 16). Medical cannabis treating at least 2.7 percent of population. The University of Sydney. https://www.sydney.edu.au/news-opinion/news/2022/12/16/medical-cannabis-treating-population.html
- Howlett, A. C., Blume, L. C., & Dalton, G. D. (2010). CB1 Cannabinoid Receptors and their Associated Proteins. Current Medicinal Chemistry, 17(14), 1382–1393. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179980/
- THC (tetrahydrocannabinol). (n.d.). Leafly. Retrieved March 26, 2024, from https://www.leafly.com/learn/cannabis-glossary/thc
- Painter, K., & Watson, S. (2024, January 9). Medical Marijuana FAQ. WebMD. https://www.webmd.com/a-to-z-guides/medical-marijuana-faq#:~:text=Benefits%20of%20Medical%20Marijuana
- Brennan, D. (2021, October 25). How Much Does Your Metabolism Slow Down as You Age? WebMD. https://www.webmd.com/healthy-aging/how-much-does-your-metabolism-slow-down-as-you-age
- Huestis, Marilyn A. (2007). Human Cannabinoid Pharmacokinetics. Chemistry & Biodiversity, 4(8), 1770–1804. https://doi.org/10.1002/cbdv.200790152
- Clinical Overview: Cannabis May Interact With Prescription Medications. (2023, September 25). Pharmacy Times. https://www.pharmacytimes.com/view/clinical-overview-cannabis-may-interact-with-prescription-medications
- Marijuana. (n.d.). Mayo Clinic. https://www.mayoclinic.org/drugs-supplements-marijuana/art-20364974#:~:text=Long%2Dterm%20marijuana%20use%20can
- Who Should Avoid Using Cannabis? | Health. (n.d.). Province of Manitoba - Health. https://www.gov.mb.ca/health/cannabis/avoid.html
- The 7 Highest THC Strains to Try in 2024. (n.d.). Leafwell. Retrieved March 26, 2024, from https://leafwell.com/blog/highest-thc-strains
- The 7 Highest THC Strains to Try in 2024. (n.d.). Leafwell. Retrieved March 26, 2024, from https://leafwell.com/blog/highest-thc-strains
- Beginner’s Guide to Cannabis Plants and Strains. (n.d.). Healthline. https://www.healthline.com/health/sativa-vs-indica#sativa
- Overview of Cannabis Routes of Administration – The Daily Duck. (n.d.). Blogs.uoregon.edu. https://blogs.uoregon.edu/articles/2023/04/20/overview-of-cannabis-routes-of-administration/
- Overview of Cannabis Routes of Administration – The Daily Duck. (n.d.). Blogs.uoregon.edu. https://blogs.uoregon.edu/articles/2023/04/20/overview-of-cannabis-routes-of-administration/
- Turner, A. R., & Agrawal, S. (2023). Marijuana. PubMed; StatPearls Publishing. https://www.ncbi.nlm.nih.gov/books/NBK430801/#:~:text=Marijuana%20can%20be%20administered%20in
- Overview of Cannabis Routes of Administration – The Daily Duck. (n.d.). Blogs.uoregon.edu. https://blogs.uoregon.edu/articles/2023/04/20/overview-of-cannabis-routes-of-administration/
- Bhaskar, A., Bell, A., Boivin, M., Briques, W., Brown, M., Clarke, H., Cyr, C., Eisenberg, E., de Oliveira Silva, R. F., Frohlich, E., Georgius, P., Hogg, M., Horsted, T. I., MacCallum, C. A., Müller-Vahl, K. R., O’Connell, C., Sealey, R., Seibolt, M., Sihota, A., & Smith, B. K. (2021). Consensus recommendations on dosing and administration of medical cannabis to treat chronic pain: results of a modified Delphi process. Journal of Cannabis Research, 3(1). https://doi.org/10.1186/s42238-021-00073-1
- Dosing Cannabis: 10 Key Things to Consider. (n.d.). Leafwell. Retrieved March 26, 2024, from https://leafwell.com/blog/dosing-cannabis-medical-marijuana-10-key-things-to-consider
- https://www.facebook.com/verywell. (2019). Can Marijuana Really Reduce Symptoms of Anxiety? Verywell Mind. https://www.verywellmind.com/marijuana-and-anxiety-1393132
- Bathula, P. P., & Maciver, M. B. (2023). Cannabinoids in Treating Chemotherapy-Induced Nausea and Vomiting, Cancer-Associated Pain, and Tumor Growth. International Journal of Molecular Sciences, 25(1), 74. https://doi.org/10.3390/ijms25010074
- Mack, A., & Joy, J. (2011). MARIJUANA AND CANCER. Nih.gov; National Academies Press (US). https://www.ncbi.nlm.nih.gov/books/NBK224387/
- Vaillancourt, R., Gallagher, S., Cameron, J. D., & Dhalla, R. (2022). Cannabis use in patients with insomnia and sleep disorders: Retrospective chart review. Canadian Pharmacists Journal / Revue Des Pharmaciens Du Canada, 155(3), 175–180. https://doi.org/10.1177/17151635221089617
- Cannabis as a Sleep Aid: Here’s What You Need to Know. (2017, September 14). Healthline. https://www.healthline.com/health/medical-marijuana/cannabis-for-sleeping#choosing-your-strain
- Wiginton, K. (n.d.). Cannabis, CBD, and Sleep. WebMD. https://www.webmd.com/sleep-disorders/features/cannabis-cbd-sleep
- Stuyt, E. (2018). The Problem with the Current High Potency THC Marijuana from the Perspective of an Addiction Psychiatrist. Missouri Medicine, 115(6), 482–486. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312155/#:~:text=This%20can%20lead%20to%20increased